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Hypothalamic transcriptome in Prader-Willi syndrome

ABSTRACT: Transcriptional analysis of brain tissue from people with molecularly defined causes of obesity may highlight novel disease mechanisms and therapeutic targets. Prader-Willi syndrome (PWS) is a genetic obesity syndrome characterised by severe hyperphagia. We performed RNA sequencing of the hypothalamus from 4 individuals with PWS and 4 age-matched controls.

PROVIDER: EGAS00001002901 | EGA |

REPOSITORIES: EGA

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