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WES of clonally related neuroblastoma and teratoma

ABSTRACT: Mature teratomas are usually benign tumors that rarely undergo malignant transformation. We report an advanced neuroblastoma arising in a mature teratoma of the ovary. Whole-exome sequencing identified extensive copy-neutral LOH in both neuroblastoma and teratoma elements, suggesting that the neuroblastoma evolved from the teratoma.

PROVIDER: EGAS00001005116 | EGA |

REPOSITORIES: EGA

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