Genomics

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MiRNA regulation of monocyte expressed inflammatory genes in patients with inflammatory bowel disease


ABSTRACT: MicroRNAs are critical regulators of gene expression controlling cellular processes including inflammation. We explored their role in the pathogenesis of inflammatory bowel disease (IBD), and identified reduced expression of miR-374a-5p in IBD monocytes that correlated with a module of up- regulated genes related to the inflammatory response.

PROVIDER: EGAS00001006157 | EGA |

REPOSITORIES: EGA

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