Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

GLASS-NL DNA-Methylation

ABSTRACT: Low-grade IDH-mutant glioma are notoriously unpredictable and knowledge on the evolutionary trajectories is limited. The GLASS-NL consortium performed methylome profiling on paired initial and recurrent IDH-mutant astrocytoma tumours to elucidate the temporal changes in DNA-methylation. Whole-exome sequencing data and RNA-sequencing data from these samples are submitted separately.

PROVIDER: EGAS00001007546 | EGA |

REPOSITORIES: EGA

ACCESS DATA

Json Xml

Similar Datasets

Mutant IDH modulates suppressive myeloid populations in malignant glioma

Project description:RNA-sequencing for myeloid inflammation-related genes was conducted on primary tumor samples from patients with IDH-wildtype glioblastoma (GBM) and grade 4 IDH-mutant astrocytoma (G4IMA). In addition, the IDH-wildtype murine glioma cell line GL261 and a strain of IDH-mutant GL261 were also sequenced using the murine counterpart of the RNA-sequencing myeloid innate immunity panel.

2024-05-29 | GSE268118 | GEO

Single cell RNA-seq analysis of IDH-mutant astrocytoma

Project description:To understand the diversity of expression states within IDH-mutant astrocytoma tumors, we profiled 6341 cells from 10 tumors by single cell RNA-seq

2017-03-31 | GSE89567 | GEO

c9380023-11c0-4e9f-9b4a-a47f689aa391 - samples

Project description:Anaplastic Astrocytoma, IDH-mutant

| EGAD00001008304 | EGA

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Project description:This multi-site, Phase 1/2 clinical trial is an open-label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen of NEO212 for the treatment of patients with radiographically-confirmed progression of Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype, and the safety, pharmacokinetics and efficacy of a repeated dose regimen of NEO212 when given with select SOC for the treatment of solid tumor patients with radiographically confirmed uncontrolled brain metastasis. The study will have three phases, Phase 1, Phase 2a and Phase 2b.

| 92735 | ecrin-mdr-crc

Homo sapiens

Project description:Single cell RNA-seq analysis of IDH-mutant astrocytoma

| PRJNA352580 | ENA

f29d05d4-6b68-463b-8db5-7368842bcf19 - samples

Project description:SF11940 snATAC Sequencing.Anaplastic Astrocytoma, IDH-mutant. Tumor location: Left Frontal. Age: 29. Sex: Male .

| EGAD00001006311 | EGA

S. coelicolor YSK3225 R5- Medium Time-course Study (Culture #2)

Project description:Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study, we employed whole-genome microarray methods to investigate the temporal transcriptome profiles of S. coelicolor A3(2) ∆absA1::apr mutant strain and compared with the M145 Wild-type strain (series submitted separately). Keywords: Time course

2007-06-14 | GSE8109 | GEO

S. coelicolor YSK3225 R5- Medium Time-course Study (Culture #1)

2007-06-14 | GSE8108 | GEO

S. coelicolor YSK4425 R5- Medium Time-course Study (Culture #1)

Project description:Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study, we employed whole-genome microarray methods to investigate the temporal transcriptome profiles of S. coelicolor A3(2) ∆afsS::apr mutant strain and compared with the M145 Wild-type strain (series submitted separately). Keywords: Time course

2007-06-14 | GSE8110 | GEO

091e45da-cca9-480e-bd2a-85fe5693706a - samples

Project description:Single cell RNA-Seq Primary diffuse astrocytoma G2. IDH mutant, ATRX mutant. Gender Male Age 34. Single Cell RNA seq from primary astrocytoma sample. NovaSeq6000 was used for RNA seq. The files uploaded are bam files created with grch38 reference through Cellranger count (10xGenomics.)

| EGAD00001005394 | EGA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data