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P2011.3.1 Copasi

ABSTRACT: P2011.3.1 Copasi

SUBMITTER: Andrew Millar

PROVIDER: 654 | FAIRDOMHub | 2019-12-20

REPOSITORIES: FAIRDOMHub

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Defining the robust behaviour of the plant clock gene circuit with absolute RNA timeseries and open infrastructure.

Flis Anna A Fernández Aurora Piñas AP Zielinski Tomasz T Mengin Virginie V Sulpice Ronan R Stratford Kevin K Hume Alastair A Pokhilko Alexandra A Southern Megan M MM Seaton Daniel D DD McWatters Harriet G HG Stitt Mark M Halliday Karen J KJ Millar Andrew J AJ

Open biology 20151001 10

Our understanding of the complex, transcriptional feedback loops in the circadian clock mechanism has depended upon quantitative, timeseries data from disparate sources. We measure clock gene RNA profiles in Arabidopsis thaliana seedlings, grown with or without exogenous sucrose, or in soil-grown plants and in wild-type and mutant backgrounds. The RNA profiles were strikingly robust across the experimental conditions, so current mathematical models are likely to be broadly applicable in leaf tis ...[more]

PMID: 26468131

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