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RNA-seq of C. elegans worms treated with RNAi toward daf-2 or cav-1 or left untreated (EV) to compare gene expression profiles

ABSTRACT: We observed functional outcomes of cav-1 knockdown and wanted to characterize changes in gene expression profiles following this manipulation. To address this, we treated nematodes with daf-2 or cav-1 RNAi and compared gene expression profiles to these of untreated worms. The knockdown of cav-1 resulted in modulation in the expression of 92 genes, and some of them overlapped with genes which were affected by knockdown of daf-2.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE100045 | GEO | 2017/06/19

SECONDARY ACCESSION(S): PRJNA390548

REPOSITORIES: GEO

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