Genomics

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The effect of SNAIL transcription factor on microRNA transcriptome in rhabdomyosarcoma


ABSTRACT: The main goal of the project was to analyze the effect of SNAIL transcription factor on microRNA expression profile in rhabdomyosarcoma (RMS) cells using the next generation sequencing. Differential expression of microRNAs between three groups was compared in RH30 alveolar RMS cells: WT (WT), shCTRL (modified with control shRNA vector) and shSNAIL (modified with shRNA against SNAIL). Different groups were compared to investigate the effect of SNAIL silencing on microRNA up- or downregulation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE100114 | GEO | 2020/07/15

REPOSITORIES: GEO

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