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Microarray CGH (aCGH) analysis of a patient with Mental Retardation (MR)

ABSTRACT: Background: Mental Retardation occurs with the prevalence of 2%-3% of general population. Molecular karyotyping by 1-Mb resolution microarray revealed that pathological genomic imbalances were found in 14%-20% of MR. Aim: The aim of this study is to find the submicroscopic rearrangements in patient with MR using the custom BAC microarray (probe spacing at 0.75 Mb throughout the human genome). Conclusion: We identified approximate 2.0-Mb deletion on 9q33.3-q34.11 in a female with MR (Patient 1). Keywords: array CGH

ORGANISM(S): Homo sapiens

PROVIDER: GSE10077 | GEO | 2008/05/11

SECONDARY ACCESSION(S): PRJNA108639

REPOSITORIES: GEO

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