Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9
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ABSTRACT: In this Study, we used RNA-targeting Cas9 (RCas9) to reverse characteristic Myotonic Dystrophy (DM1) cellular phenotypes such as elimination of RNA foci, MBNL relocalization, and reversal of transcriptome-wide splicing.
ORGANISM(S): Homo sapiens
PROVIDER: GSE100943 | GEO | 2017/08/10
SECONDARY ACCESSION(S): PRJNA393468
REPOSITORIES: GEO
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