Transcriptomics

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Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9


ABSTRACT: In this Study, we used RNA-targeting Cas9 (RCas9) to reverse characteristic Myotonic Dystrophy (DM1) cellular phenotypes such as elimination of RNA foci, MBNL relocalization, and reversal of transcriptome-wide splicing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE100943 | GEO | 2017/08/10

SECONDARY ACCESSION(S): PRJNA393468

REPOSITORIES: GEO

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