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Host response to IAV infections in human patients

ABSTRACT: Using influenza infection as a disease model, we used a systems biology approach to analyse host response and to identify immune pathways that might contribute to disease progression. We recruited influenza patients with varying severity of infection (n=154) and collected peripheral blood samples within 24 hours of their presentation to hospitals. Gene-expression arrays of these samples were analysed using weighted gene co-expression network analysis to detect disease-driving modules. These modules were then ranked based on the weight of their contribution to disease progression and fatality.

ORGANISM(S): Homo sapiens

PROVIDER: GSE101702 | GEO | 2019/04/15

REPOSITORIES: GEO

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