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Human HCT-116 cells: Control vs CDK2 knockout, NU6102 treated and resistant cells

ABSTRACT: Transcriptional profiling of isogenic human colorectal cancer cell line HCT-116, comparing parental cells, CDK2 knockout cells, cells treated with the CDK2-selective inhibitor NU6102 and cells resistant to 50µM NU6102. The aim was to compare effects of loss of CDK2 gene or kinase activity and determine potential mechanisms of inhibitor-resistance

ORGANISM(S): Homo sapiens

PROVIDER: GSE102165 | GEO | 2017/08/03

SECONDARY ACCESSION(S): PRJNA396897

REPOSITORIES: GEO

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