Transcriptomics

Dataset Information

0

Gene expression in AES-2 clonal isolates of Pseudomonas aeruginosa


ABSTRACT: Pseudomonas aeruginosa (P. aeruginosa) lung infection is a significant cause of mortality in patients with cystic fibrosis (CF). Most CF patients acquire unique P. aeruginosa strains from the environment; however clonal strains have been identified in CF communities in several countries. Two clonal strains infect 10% to 40% of patients in three CF clinics in mainland eastern Australia. The expression profiles of four planktonically-grown isolates of one Australian clonal strain (AES-2), and four non–clonal CF P. aeruginosa isolates were compared to each other and to the reference strain PAO1 using the Affymetrix P. aeruginosa PAO1 genome array, to gain insight into properties mediating the enhanced infectivity of AES-1. The isolates were subsequently grown as 3-day old biofilms and similarly extracted for RNA and compared as above. Data analysis was carried out using BIOCONDUCTOR software. Keywords: Comparative strain hybridization

ORGANISM(S): Pseudomonas aeruginosa

PROVIDER: GSE10304 | GEO | 2009/02/05

SECONDARY ACCESSION(S): PRJNA108523

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2008-12-05 | GSE6122 | GEO
2015-10-14 | PXD002865 | Pride
2011-07-15 | E-GEOD-28152 | biostudies-arrayexpress
2010-06-08 | E-GEOD-21966 | biostudies-arrayexpress
2017-08-29 | PXD007233 | Pride
2022-05-09 | PXD025827 | Pride
2015-12-02 | GSE74445 | GEO
2011-12-31 | GSE33275 | GEO
2010-05-25 | GSE21966 | GEO
2019-06-24 | PXD006742 | Pride