Transcriptomics

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Expression data of A549 cells treated with 2 µM of HCI-2509 for 48 h


ABSTRACT: Inhibition of LSD1 is a novel option for treatment of lung cancer. Using HCI-2509, a specific inhibitor of LSD1, results in a cell cycle arrest as wel as a shift in global histone 3 lysine 4 and lysine 9 dimethylation pattern. Using microarrays we aim to illucidate the changed transcriptome upon treatement of HCI-2509 in lung adenocarcinoma cell line A549.

ORGANISM(S): Homo sapiens

PROVIDER: GSE103256 | GEO | 2017/08/30

SECONDARY ACCESSION(S): PRJNA400630

REPOSITORIES: GEO

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