Transcriptomics

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Expression data from normal weight/obese and sham/injured female C57BL/6J mice


ABSTRACT: Injury of skeletal muscle is a common occurence affecting millions worldwide. Injuries usually are not major incisions into daily life, however, the underlying health varies e. g. due to obesity. Obesity is usually accompanied by excessive and dysfunctional lipid depots, chronic low-grade inflammation as well as several co-morbidities, which are able to impair the regeneration of skeletal muscle. A blunt injury approach was used to damage mouse skeletal muscle of the extensor iliotibialis anticus in both obese and normal weight C57BL/6J mice. Microarray analysis was used to assess the molecular fingerprint in different stages of muscle regeneration while observing different health conditions.

ORGANISM(S): Mus musculus

PROVIDER: GSE103726 | GEO | 2018/02/09

REPOSITORIES: GEO

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