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Genome-wide analysis of the histone variant H3mm7

ABSTRACT: We identified a histone H3.3 sub-variant, H3mm7, to be specifically expressed in skeletal muscle satellite cells. H3mm7 knockout mice demonstrated an essential role of H3mm7 in skeletal muscle regeneration. Chromatin analysis revealed that H3mm7 facilitates transcription by forming an open chromatin structure around promoter regions including those of myogenic genes.

ORGANISM(S): Mus musculus

PROVIDER: GSE104389 | GEO | 2018/02/27

REPOSITORIES: GEO

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Notch signaling/MyoD double deficient embryonic muscle progenitors

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