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RNA-seq of Injured Nerve in Schwann cell conditional knockout of Eed

ABSTRACT: The goal of the experiment was to determine the role of the polycomb repressive complex 2 in the nerve injury response in peripheral nerve. A Schwann cell specific knockout of the Eed subunit of PRC2 was generated to compare with wild type mice in sham and injured mice at 1d and 14d timepoints after nerve injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE106969 | GEO | 2018/01/01

SECONDARY ACCESSION(S): PRJNA418689

REPOSITORIES: GEO

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RNA-seq of Injured Nerve in Schwann cell conditional knockout of Eed

Project description:RNA-seq of Injured Nerve in Schwann cell conditional knockout of Eed

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c-JUN REPROGRAMS SCHWANN CELLS OF INJURED NERVES TO GENERATE A REPAIR CELL ESSENTIAL FOR REGENERATION

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