Methylation profiling

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DNA methylation analysis of human keratoconus corneas using RRBS sequencing


ABSTRACT: Keratoconus (KTCN) is a complex degenerative eye disorder resulting in loss of visual function. It is known, that its development is affected by both genetic and environmental or behavioral components. In order to verify if DNA methylation may also play a role in KTCN development, reduced representation bisulfite sequencing (RRBS) of human corneas obtained from five KTCN and five non–KTCN individuals was performed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE107189 | GEO | 2019/04/05

REPOSITORIES: GEO

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