Transcriptomics

Dataset Information

0

Mononuclear phagocytes locally specify and adapt their phenotype in the inflamed central nervous system, blood monocyte and brain microglia expression data


ABSTRACT: We introduce an in vivo imaging approach that allows us to temporally and spatially resolve the evolution of iNOS and Arginase-positive phagocyte phenotypes in a murine MS model. We show that the polarization of individual phagocytes is established after CNS entry, is dependent on the CNS compartment and can be adapted as inflammatory lesions move from expansion to resolution. Our study thus provides a first real-time analysis of phagocyte specification in the intact CNS.

ORGANISM(S): Mus musculus

PROVIDER: GSE107790 | GEO | 2018/09/05

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2018-09-05 | GSE98589 | GEO
2018-09-05 | GSE107791 | GEO
2018-09-05 | GSE107792 | GEO
| PRJNA421374 | ENA
2019-07-10 | PXD010245 | Pride
2008-04-05 | E-GEOD-7769 | biostudies-arrayexpress
| PRJNA421379 | ENA
2008-03-14 | GSE7769 | GEO
| PRJNA421368 | ENA
2023-05-30 | GSE206205 | GEO