PBMC gene expression from Crohn's disease patients before Infliximab therapy.
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ABSTRACT: About 40% IBD patients treated with anti-TNF antibodies do not respond to therapy. Baseline biomarkers of response are therefore of interest. By combining computational deconvolution of gene expression and meta-analysis approaches we identified cellular biomarkers in tissue (validated in 2 cohorts by IHC of biopsies), and investigated associated gene biomarkers in blood. This dataset provides data from the validation cohort III (blood).
ORGANISM(S): Homo sapiens
PROVIDER: GSE107865 | GEO | 2018/02/01
REPOSITORIES: GEO
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