Transcriptomics

Dataset Information

0

Chronic potassium chloride (KCl) treatment induced gene expression changes in Drosophila head


ABSTRACT: We have recently developed a Drosophila behavioral- and transcriptomic- based (systems) model of chronic pentylenetetrazole induced locomotor plasticity. Pharmacological validation at behavioral level and at the level of fly head microarray gene expression shows that the model is of potential value in screening of compounds for detecting antiepileptic, antiepileptogenic, disease-modifying and neuroprotective activities. While screening compounds using this model at behavioral level, potassium chloride (KCl) was identified as having therapeutic potential. Examination of transcriptomic changes induced by KCl in fly head further supports its potential use as a therapeutic agent in neurological and neuropsychiatric conditions. Keywords: Drug Response

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE10808 | GEO | 2008/03/18

SECONDARY ACCESSION(S): PRJNA107397

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2010-05-25 | E-GEOD-10808 | biostudies-arrayexpress
2007-10-05 | GSE7203 | GEO
2007-10-05 | GSE7202 | GEO
2007-10-05 | GSE7200 | GEO
2007-10-05 | GSE7199 | GEO
2007-10-04 | GSE7488 | GEO
2007-10-02 | GSE7156 | GEO
2007-10-02 | GSE7120 | GEO
2008-03-25 | GSE10852 | GEO
2008-05-03 | GSE10988 | GEO