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Early response of human ovarian and fallopian tube surface epithelial cells to norepinephrine

ABSTRACT: The purpose of this study is to understand the effects of adrenergic signaling on the transcriptome of cell line models postulated to be the cells of origin of epithelial ovarian cancers using RNA-Seq. Here we explored the effects of the stress-related hormone, norepinephrine, on normal human ovarian and fallopian tube surface epithelial cellss. We investigated the early transcriptional response to norepinephrine in normal immortalized ovarian surface epithelial cells and fallopian tube secretory cells. RNA-Seq data of treated and untreated cells were analyzed to identify genes with differential expression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE108084 | GEO | 2018/05/25

REPOSITORIES: GEO

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