TIP60 represses activation of endogenous retroviral elements
Ontology highlight
ABSTRACT: We found that the loss of TIP60 de-represses retrotransposon elements genome-wide, which in turn activate the cellular response to pathogens mediated by STING, culminating in an induction of Interferon Regulatory Factor 7 (IRF7) and associated inflammatory response.
ORGANISM(S): Homo sapiens
PROVIDER: GSE108834 | GEO | 2019/12/01
REPOSITORIES: GEO
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