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Genome-wide maps of c-Myc binding sites in myoblasts and myotubes

ABSTRACT: By applying ChIP-seq, we generated genome-wide maps of c-Myc in skeletal myoblasts and myotubes. We found that c-Myc binds to 19354 confident target with a large portion residing in the intergenic regions. In addition, c-Myc was found to regulate many loci. Further detailed study revealed that c-Myc can regulate some genes, miRNAs, and lincRNAs which are fucntional in skeletal myogenesis. In this study, we identified a c-Myc induced regulatory pathway in myogensis.

ORGANISM(S): Gallus gallus

PROVIDER: GSE109223 | GEO | 2018/01/17

SECONDARY ACCESSION(S): PRJNA430194

REPOSITORIES: GEO

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