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High throughput quantitative whole transcriptome analysis of adult mouse distal lung mesenchyme

ABSTRACT: We used microfluidic single cell RNA-seq on 47 individual mouse lung mesenchymal cells at adulthood to measure the transcriptional state. We were able to classify these cells into distinct populations as well as map their signaling interactions with the distal lung epithelium and endothelium. In this manner, single cell RNA-seq can be used to unbiasedly determine the signals the dictate construction and maintenance of the alveolus.

ORGANISM(S): Mus musculus

PROVIDER: GSE109444 | GEO | 2018/02/19

REPOSITORIES: GEO

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