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Global gene expression profile of CD8+ TILs from WT and B7S1 KO mice

ABSTRACT: B7S1 negatively regulates T cells and its expression correlates with poor prognosis of cancer patients. In order to understand how B7S1 signaling contributes to dysfunction of CD8+ T cell in the TME, we conducted transcriptional analysis of OVA-specific CD8+ TILs and different TIL subsets from E.G7-bearing WT and B7S1 KO mice (Day 21).

ORGANISM(S): Mus musculus

PROVIDER: GSE110249 | GEO | 2018/04/03

REPOSITORIES: GEO

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Epigenetic profiling of OVA-specific CD8+ TILs from mice treated with control, anti-B7S1, anti-PD-1 or anti-B7S1+anti-PD-1 antibodies

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