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Mycobacterium tuberculosis cording in lymphatic endothelial cells (hLEC)

ABSTRACT: Mycobacterium tuberculosis (Mtb) displayed cording phenotypes during intracellular infection. RNA-Seq was used to identify transcriptional programmes expressed by hLEC that actviates pathways relating to cellular pro-survival and cyosolic surveillance of intracellular Mtb. Mtb cording was found to be a mechanism to evade xenophagy in the cytosol of endothelial cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE110564 | GEO | 2020/06/04

REPOSITORIES: GEO

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