Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of brain tissue from Parkinson's disease patients [coding exome RNA-seq]

ABSTRACT: High throughput sequencing of coding exome RNA from cingylate gyrus brain tissue obtained from control- and Parkinson´s disease patients. In the Parkinson´s disease affected tissue, changes are present that are known to be related to the pathogenesis of neurodegenerative diseases.

ORGANISM(S): Homo sapiens

PROVIDER: GSE110716 | GEO | 2018/10/08

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Small RNA profiling from cultured cells and tissues derived from Parkinson's disease patient [small RNA-seq]

Project description:High throughput sequencing of small RNAs (mature miRNA and piRNA/piRNA-like molecules) from control- and sporadic Parkinson´s disease patient derived fibroblasts (n=15), induced pluripotent stem cells (n=26) and differentiated midbrain neurons (n=10). In parallel, cingulate gyrus samples from eight control- and eight Parkinson´s disease patients obtained from the Netherlands Brain Bank were sequenced. We found significant differences between the groups in every cell type and in tissue.

2018-10-08 | GSE110719 | GEO

RNA-seq of cultured cells derived from Parkinson's disease patients [PolyA RNA-seq]

Project description:High throughput sequencing of poly-A RNA from control- and sporadic Parkinson´s disease patient derived fibroblasts (n=15), induced pluripotent stem cells (n=31) and differentiated midbrain neurons (n=15). Fibroblasts and iPSCs do not show major differences on single gene level. In contrast, midbrain neurons derived from Parkinson´s disease patients show changes known to be associated with neurodegenerative diseases.

2018-10-08 | GSE110717 | GEO

RNA-seq of brain tissue from Parkinson's disease patients [coding exome RNA-seq]

Project description:RNA-seq of brain tissue from Parkinson's disease patients [coding exome RNA-seq]

| PRJNA434416 | ENA

Transcriptional analysis of putamen in Parkinson's disease

Project description:Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects Published work contains more information on Parkinson and Control groups

2010-03-23 | E-GEOD-20291 | biostudies-arrayexpress

Transcriptional analysis of whole substantia nigra in Parkinson's disease

2010-03-23 | E-GEOD-20292 | biostudies-arrayexpress

Transcriptional analysis of prefrontal area 9 in Parkinson's disease

2010-02-22 | E-GEOD-20168 | biostudies-arrayexpress

Transcriptional analysis of putamen in Parkinson's disease

Project description:Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects

2010-03-12 | GSE20291 | GEO

Transcriptional analysis of whole substantia nigra in Parkinson's disease

Project description:Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects

2010-03-12 | GSE20292 | GEO

Transcriptional analysis of prefrontal area 9 in Parkinson's disease

Project description:Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects

2010-02-04 | GSE20168 | GEO

Cortical hypermethylation across an extended region spanning the HOXA gene cluster on chromosome 7 is robustly associated with Alzheimer's disease neuropathology

Project description:Alzheimer's disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. We undertook an epigenome-wide association study across three independent brain tissue cohorts (total n = 999) to identify differential DNA methylation associated with neuropathology in the superior temporal gyrus and prefrontal cortex. We present robust evidence for elevated DNA methylation associated with AD neuropathology across an extended region spanning the HOXA gene cluster on chromosome 7. Prefrontal cortex and superior temporal gyrus tissue from 147 individuals with varying levels of AD pathology. DNA modifications for these samples were quantified using the Illumina Infinium Human 450K Methylation Array.

2016-08-01 | E-GEOD-80970 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data