Transcriptomics

Dataset Information

0

Expression data from classical dendritic cells isolated from mouse lymph nodes


ABSTRACT: Dendritic cells increase expression of pro-inflammatory cytokines and chemokines and undergo metabolic reprogramming upon TLR activation. Mice fed conventional diet (CD) or 60% high-fat diet (HFD) were treated by skin application of imiquimod (IMQ) during 6 days and classical dendritic cells (cDC) were isolated from inguinal lymph nodes (iLN) to reveal inflammatory and metabolic pathways that are sensitive to TLR7/8 activation and a high fatty acid environment. We used microarray to identify pathways in classical dendritic cells from IMQ-treated mice that link inflammation and metabolism in a high fatty acid environment.

ORGANISM(S): Mus musculus

PROVIDER: GSE110963 | GEO | 2019/06/30

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-06-30 | GSE110962 | GEO
2019-06-30 | GSE68750 | GEO
2022-12-31 | GSE212126 | GEO
2016-09-07 | E-GEOD-74528 | biostudies-arrayexpress
2020-03-30 | GSE142345 | GEO
2012-02-08 | E-GEOD-15940 | biostudies-arrayexpress
2012-02-08 | GSE15940 | GEO
2014-08-28 | E-GEOD-60804 | biostudies-arrayexpress
2017-10-06 | GSE104603 | GEO
2007-12-13 | E-GEOD-7699 | biostudies-arrayexpress