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Epigenetic changes in amygdala and cortex of fear-conditioned and ErbB4 Knock-out mice

ABSTRACT: Chromatin accessibility provides an important window into the regulation of gene expression. Recently, the Assay of Transposase Accessible Chromatin with sequencing (ATAC-seq) was developed to profile genome-wide chromatin accessibility. Here we applied a read-downsampling approach to call robust ATAC-seq peaks in order to profile the regions of differential chromatin accessibility of central amygdala and cortex between different experimental conditions; fear-conditioned vs. control mice and ErbB4 knock-out vs. wild-type mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE111021 | GEO | 2019/02/21

REPOSITORIES: GEO

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