Transcriptomics

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Effect of 9 days of inhibited GDNF signaling on the transcriptome of the mouse testis


ABSTRACT: In the normal adult testis GDNF specifically targets spermatogonial stem cells and early progenitor spermatogonia. Inhibition of GDNF signaling for 9 days alters only 171 of the 15,000 transcripts expressed in the mouse testis. Many of these transcripts are known to be expressed by the spermatogonial stem cells. One transcript that is affected is Kif26A, a known suppressor of GDNF signaling.

ORGANISM(S): Mus musculus

PROVIDER: GSE111487 | GEO | 2021/01/25

REPOSITORIES: GEO

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