Expression data from podocyte injured glomerulus
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ABSTRACT:
ORGANISM(S): Mus musculus
PROVIDER: GSE112116 | GEO | 2019/03/18
REPOSITORIES: GEO
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Project description:The role of the renin-angiotensin system in chronic kidney disease involves multiple peptides and receptors. Exerting antipodal pathophysiological mechanisms, renin inhibition and AT1 antagonism ameliorate renal damage. This is a comparison between the renin inhibitor aliskiren with the At1 antagonist losartan in mice with chronic kidney disease due to renal ablation. Renal tissue from ablated mice was used after 6-week treatment with either 500 mg/l losartan or 50 mg/kg aliskiren per day (n = 5)
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Project description:Expression data from podocyte injured glomerulus
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