Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (Methylation)

ABSTRACT: We fine-mapped DNA methylation in neuronal nuclei (NeuN+) isolated by flow cytometry from post-mortem frontal cortex of the brain of individuals diagnosed with schizophrenia, bipolar disorder, and controls (n=29, 26, and 28 individuals).

OTHER RELATED OMICS DATASETS IN: PXD012786

ORGANISM(S): Homo sapiens

PROVIDER: GSE112179 | GEO | 2019/05/03

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (Bisulfite-Seq)

Project description:We fine-mapped DNA methylation in neuronal nuclei (NeuN+) isolated by flow cytometry from post-mortem frontal cortex of the brain of individuals diagnosed with schizophrenia, bipolar disorder, and controls (n=29, 26, and 27 individuals).

2019-05-03 | GSE112524 | GEO

DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (RNA-Seq)

2019-05-03 | GSE112523 | GEO

DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder

Project description:DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder

| PRJNA448067 | ENA

DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (Methylation)

Project description:DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (Methylation)

| PRJNA445175 | ENA

Gene expression profiles of patients with schizophrenia, bipolar disorder and healthy controls

Project description:Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric conditions, with a lifetime prevalence of about 1%. Both disorders have a neurodevelopment component, with onset of symptoms occurring most frequently during late adolescence or early adulthood. Genetic findings indicate the existence of an overlap in genetic susceptibility across the disorders. These gene expression profiles were used to identify the molecular mechanisms that differentiate SZ and BP from healthy controls but also that distinguish both from healthy individuals. They were also used to expand an analysis from an experiment that searched molecular alterations in human induced pluripotent stem cells derived from fibroblasts from control subject and individual with schizophrenia and further differentiated to neuron to identify genes relevant for the development of schizophrenia (GSE62105). Brain tissue (frontal cortex) from 30 healthy controls, 29 bipolar disorder patients and 29 schizophrenia patients were analyzed. The reference is an in-house pool of RNA extracted from 15 human cell lines.

2014-10-11 | E-GEOD-62191 | biostudies-arrayexpress

DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (Bisulfite-Seq)

Project description:DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (Bisulfite-Seq)

| PRJNA448068 | ENA

DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (RNA-Seq)

Project description:DNA methylation in neurons from post-mortem brains in schizophrenia and bipolar disorder (RNA-Seq)

| PRJNA448069 | ENA

Genotypes of case-control samples in major psychosis

2019-05-03 | GSE113093 | GEO

Mitochondrial Abnormalities in Schizophrenia and Bipolar Disorder

Project description:Mitochondrial Abnormalities in Schizophrenia and Bipolar Disorder

| PRJNA719179 | ENA