Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Microarray expression profile and functional analysis of circular RNAs in plasma for Esophageal Squamous Cell Carcinoma

ABSTRACT: The purpose of this study is to explore the circRNAs expression profiles in the plasma from esophageal squamous cell carcinoma (ESCC) patients.The purpose of this study is to explore the circRNAs expression profiles in the plasma from esophageal squamous cell carcinoma (ESCC) patients.

ORGANISM(S): Homo sapiens

PROVIDER: GSE112496 | GEO | 2021/03/23

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Identification of the regulation of circMAN1A2-miRNA in esophageal squamous cell carcinoma.

Project description:ESCC (Esophageal squamous cell carcinoma) is a common malignant tumor with high morbidity and mortality. CircRNAs (Circular RNAs) play important roles in various cancers including ESCC, the role of circMAN1A2(CircRNA mannosidase alpha class 1A member 2) in ESCC has not been sufficiently elucidated. The purpose of this study is to explore the biological function and potential mechanism of circMAN1A2 in ESCC, so as to provide a solid theoretical basis for circRNAs as a new target for diagnosis and treatment of ESCC.

2022-10-17 | GSE215844 | GEO

Microarray expression profile of micro RNAs in serum for Esophageal Squamous Cell Carcinoma

Project description:The purpose of this study is to explore the miRNAs expression profiles in the serum from esophageal squamous cell carcinoma (ESCC) patients.

2019-02-07 | GSE112840 | GEO

Microarray expression profile of microRNAs in Esophageal Squamous Cell Carcinoma

Project description:The purpose of this study is to explore the miRNAs expression profiles from esophageal squamous cell carcinoma (ESCC) and matched normal adjacent tissue.

2022-02-11 | GSE145198 | GEO

circ-GSK3beta Promotes metastasis in esophageal squamous cell carcinoma by targeting GSK3beta to augment beta-catenin Signaling

Project description:Circular RNAs, a novel class of noncoding RNAs, have recently drawn lots of attention in the pathogenesis of human cancers. However, the role of circRNAs in esophageal squamous cell carcinoma remains unclear. In this study, we aimed to identify novel circRNAs that regulate ESCC progression and explored their regulatory mechanisms and clinical significance in ESCC. We found that CircGSK3beta exerts critical roles in promoting ESCC metastasis and may serve as an exploitable therapeutic target for patients with ESCC. The plasma level of circGSK3beta have promising potential to serve as a novel diagnostic and prognostic biomarker for ESCC detection.

2019-11-25 | GSE131969 | GEO

Profiling circular RNA in esophageal squamous cell carcinoma (ESCC) with lymph node metastasis

Project description:Circular RNAs (circRNAs) have been identified as a novel class of non-conding RNAs, which are stable and have covalently single-stranded loop configuration.With the improvement of RNA-sequencing and bioimofrmatics, numerous dysregulated expression of circRNAs has been identified in kinds of physiological and pathological processes, especially in tumorigenesis. To date, however, the discovery of cirtical circRNA abnormalities, as well as their functions and underlying mechanisms, in the progress of esophageal squamous cell carcinoma (ESCC), is still unknown.

2021-08-31 | GSE150476 | GEO

Expression data in ezrin-knockdown ec109 cells(PSE1) and control(PS)

Project description:Ezrin belongs to the ezrin¨Cradixin¨Cmoesin (ERM) family proteins, which cross-link actin cytoskeleton and plasma membrane, and is actively involved in regulating the growth and metastatic capacity of cancer cells. Esophageal squamous cell carcinoma (ESCC) is one of the most fatal malignancies in the world and the expression of ezrin in ESCC has been described only recently, but its roles and mechanism still remained unclear. we have used the pSUPER RNAi system to stably suppress the expression of the ezrin gene in EC109, an esophageal squamous carcinoma cell line, and then cDNA microarray was performed to explore some changed genes with ezrin silence. Keywords: Gene expression after RNAi

2006-11-09 | GSE6233 | GEO

Gene expression in normal and tumoral esophageal squamous cell lines

Project description:This study was designed to identify genes aberrantly expressed in esophageal squamous cell carcinoma (ESCC) cells. Three esophageal squamous cell carcinoma-derived cell lines and one normal human esophageal squamous cell line were analyzed.

2014-09-20 | E-GEOD-61587 | biostudies-arrayexpress

Differential protein expression between ESCC and normal tissues

Project description:To understand the difference of protein expression between paired esophageal squamous cell carcinoma (ESCC) and adjacent normal tissues, we collected 10 paired ESCC and normal tissues from surgical resected specimems for high-throughput proteomic experiments. From comparative analysis, the dysregulated signaling pathways in ESCC could be uncovered.

2020-08-11 | PXD019834 | Pride

Gene expression changes upon CD63 knockdown in esophageal squamous cell carcinoma cell lines

Project description:The purpose of this analysis is to analyze the changes in gene expression that occur in cancer cells when CD63 is knocked down in esophageal squamous cell carcinoma (ESCC) cell lines. We performed a comprehensive analysis of mRNA in CD63 knockdown human ESCC cell lines (TE2, TE15) using microarrays.

2024-11-05 | GSE280961 | GEO