Transcriptomics

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HIV-1-driven aberrant host gene expression may contribute to HIV-1 persistence


ABSTRACT: Using HIV-1 RNASortSeq, we identified HIV-1-infected cells containing inducible HIV-1 for RNAseq from resting CD4+ T cells treated with PMA/ionomycin for 16 hours from eight antiretroviral therapy treated, virally suppressed, HIV-1-infected individuals. Using custom bioinformatic pipeline, we identified HIV-1 genomic RNA, host RNA and HIV-1-host chimeric RNA junctions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE112576 | GEO | 2021/04/01

REPOSITORIES: GEO

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