Transcriptomics

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Sufu and Spop cooperate to suppress SHH medulloblastoma tumorigenesis via regulation of Gli2 protein stability [RNA-seq]


ABSTRACT: GLI2 overexpression is a hallmark in SHH subgroup of medulloblastoma (SHH MB). Here we profile the transcriptome of two mouse models of SHH MB expressing high Gli2: SmoM2 overexpression and Sufu;Spop double knockout MB.

ORGANISM(S): Mus musculus

PROVIDER: GSE112772 | GEO | 2018/12/13

REPOSITORIES: GEO

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