Transcriptomics

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Gene expression profile of germinal center B cells lacking Miz1 interaction with Myc


ABSTRACT: Splenic germinal center B cells (B220pos, CD19pos, CD38 low, FAS high) were isolated from animals 10 days sheep red blood cell immunised animals using flow cytometry cell sorter. Animals carry a combination of alleles that allows germinal center B cell deletion of endogenous Myc allele and simultaneous conditional overexpression of human MYC in its wild-type for or mutant form in which a valine in residue 394 has been substituted by an aspartic acid.

ORGANISM(S): Mus musculus

PROVIDER: GSE112844 | GEO | 2022/04/20

REPOSITORIES: GEO

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