Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines

ABSTRACT: RNA sequencing technology has been carried out in order to compare mRNA expression changes in epithelial BxPC-3 versus mesenchymal S2-007 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE113259 | GEO | 2018/04/18

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines

Project description:RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines

| PRJNA450600 | ENA

Transcription profiling by array of two sub-clones of the SUIT2 pancreatic cancer cell line (S2-007 and S2-028) in order to identify metastasis-associated candidate genes.

Project description:S2-007 and S2-028 are cell lines derived from the same primary pancreatic adenocarcinoma, but displying strong differences in their invasive and metastatic potential both in vitro and in vivo. Three independent preparations each of the highly metastatic S2-007 and the low metastatic S2-028 cell line grown in 2D cell culture (DMEM (Gibco, Invitrogen, Carlsbad, CA) supplemented with 10% (v/v) fetal bovine serum (PAA, Pasching, Austria) in a humidified atmosphere and 5% CO2, 95% air at 37°C) were analyzed by expression profiling.

2015-02-25 | E-MTAB-3344 | biostudies-arrayexpress

si RNA interference of Hepatitis B viral gene expression

Project description:Gene expression profiling comparisons of HepG2.2.15 or PLC/PRF/5 cells either mock (M) transfected or transfected with 0.2 microM S2 RNA or Scrambled (SCR) siRNA were carried out in duplicate 48 hours after transfection. The experiments were carried out in duplicate (a and b). The following combinations of RNA were used on 2 slides each: 1. 2.2.15 cells: mock transfection (reference) versus S2 treatment (test) 2. 2.2.15 cells: mock transfection (reference) versus Scr treatment (test) 3. 2.2.15 cells: Scr treatment (reference) versus S2 treatment (test) 4. PLC/PRF/5 cells: mock transfection (reference) versus S2 treatment (test) 5. PLC/PRF/5 cells: mock transfection (reference) versus Scr treatment (test) 6. PLC/PRF/5 cells: Scr treatment (reference) versus S2 treatment (test) A stimulus or stress experiment design type is where that tests response of an organism(s) to stress/stimulus. e.g. osmotic stress, behavioral treatment Keywords: stimulus_or_stress_design

2006-01-07 | GSE3992 | GEO

Chip array data for Suit2-007 cells treated by riproximin (Rpx)

Project description:We report the effect of Rpx on human PDAC Suit2-007 cells after 48h time point

2020-09-01 | GSE152304 | GEO

RNA-seq of human pancreatic cell lines, L3.6pl and BxPC-3, upon knockdown of p63 for 48 hours compared to siControl

Project description:Investigation of gene expression profile changes upon down regulation of p63 in L3.6pl and BxPC-3 cell lines which are representative of the squamous molecular subtype in pancreatic cancer

2018-12-18 | E-MTAB-7033 | biostudies-arrayexpress

Transcription profiling of human wildtype DPC4 or empty vector expressed in pancreatic cancer BxPC-3 cell lines

Project description:Wildtype DPC4 or empty vector expressed in pancreatic cancer BxPC-3 cell lines

2008-06-12 | E-GEOD-2646 | biostudies-arrayexpress

The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of Amyotrophic Lateral Sclerosis

Project description:Our study investigated the therapeutic potential of OKN-007 in the SOD1 G93A mouse model of amyotrophic lateral sclerosis (ALS). The impact of OKN-007, known for its antioxidant, anti-inflammatory, and neuroprotective properties, was tested at two doses (150 mg/kg and 300 mg/kg) at onset and late-stage disease. Results demonstrated a significant delay in disease progression at both doses, with treated mice showing a slower advance to severe disease stages compared to untreated controls. Transcriptomic analysis using bulk RNA sequencing identified dysregulated genes in G93A mice that were restored by OKN-007 treatment and pathways that showed altered expression in response to OKN-007. Overall, our findings suggest that OKN-007 holds potential as a disease-modifying treatment for ALS, although further research is needed to optimize dosing regimens and understand its long-term effects.

2024-11-10 | GSE281064 | GEO

Serotonin effect on Bxpc-3 pancreatic adenocarcinoma cell line.

Project description:Analysis of Bxpc-3 cells treated with serotonin under metabolic stress induced by serum deprivation. Serotonin (5-HT), a well-known neuromodulator with both neurotransmitter and neuroendocrine functions, is also involved in tumorigenesis. Results provide insight into molecular basis of serotonin in pancreatic cancer.

2016-05-12 | GSE81355 | GEO

Rhizobium sp. 007

Project description:Rhizobium sp. 007 Genome sequencing

| PRJNA674303 | ENA

si RNA interference of Hepatitis B viral gene expression

2006-01-06 | E-GEOD-3992 | biostudies-arrayexpress