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Genomic distribution of H3K9me2 in wild-type vs. arle-14 mutant C. elegans embryos

ABSTRACT: We discovered arle-14/B0336.5 as a critical gene for H3K9 di-methylation. To test the hypothesis that ARLE-14 targets the H3K9 methyltransferase MET-2 to specific loci, we compared the distribution of H3K9me2 in wild-type and arle-14 mutants by ChIP-Seq. Our results reveal that H3K9me2 genomic distribution is similar in wild-type vs. mutants and ARLE-14 is not required for targeting MET-2.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE113841 | GEO | 2018/08/22

REPOSITORIES: GEO

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