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Heavy chain immunoglobulin sequencing of Lyme disease PBMCs

ABSTRACT: Lyme disease (Borrelia burgdorferi infection) is increasingly recognized as a significant source of morbidity world-wide. Here, we investigated B cell responses to Lyme disease through molecular identifier-enabled antibody heavy chain sequencing of bulk B cells from PBMCs. Single-cell immunoglobulin sequencing of paired heavy- and light-chain genes from this project will also be separately deposited. Additional information regarding patient characteristics and overlap with other data from the SLICE study is available upon request.

ORGANISM(S): Homo sapiens

PROVIDER: GSE113938 | GEO | 2018/12/21

REPOSITORIES: GEO

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Single cell paired heavy- and light-chain immunoglobulin sequencing of sorted Lyme disease plasmablasts

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