Transcriptomics

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Hemispheric lateralization of gene expression profile in stressed mice


ABSTRACT: Chronic stress increases the risk of emotional disorders by altering brain structure and function. Patients with post-traumatic stress disorder (PTSD) or depressions show activity difference between the two hemispheres in the prefrontal cortex (PFC) but molecular targets associated with this laterality remains unclear. Here, we reveal that chronic social defeats later gene-expression profile differentially between the left and right medial prefrontal cortices (mPFC) in mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE114224 | GEO | 2021/06/30

REPOSITORIES: GEO

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