Transcriptomics

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Coordinated regulation of pre-mRNA splicing by the SFPS-RRC1 complex to promote photomorphogenesis in Arabidopsis


ABSTRACT: We report the application of illumina high throughput RNA sequencing for rrc1-3 mutants in both light and dark conditions(three replicates under each condition) in Arabidopsis. By obtaining over 100 million reads (150bp paired_end) for each rRNA depleted lib, we compared the transcriptome profile between rrc1-3 mutant and Col-0 wild type light and dark conditions. We find that genome wide spliciing activities are general defective in rrc1-3 mutant comparing to Col-0 wild type, which indicates the importance of post-transcriptional processing on gene expression regulation. In addition, the sequencing data also indicates light signal probably regulates both splicing cascade and transcriptional cascade to control the downstream gene expression.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE114995 | GEO | 2019/09/25

REPOSITORIES: GEO

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