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Type 1 interferon signaling is crucial from the loss of tolerance nd the development of autoreactive B cells.

ABSTRACT: The transcriptomes of FACS-sorted B220+GL7+CD95+ germinal center B cells and B220+GL7-CD95- non-germinal center B cells from lupus-prone B6.Sle1b were compared to the same cell types in B6.Sle1b mice without the type 1 interferon receptor (B6.Sle1b.IFNaR1-/-).

ORGANISM(S): Mus musculus

PROVIDER: GSE115349 | GEO | 2018/12/25

REPOSITORIES: GEO

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