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MRNA expression modification after XRN1 depletion in Hela Cells

ABSTRACT: RNA homeostasis, a process maintained through a balance between transcription and decay, plays a critical role for most cellular functions. The conserved XRN and DIS3 families are major exoribucleases involved in this RNA turnover. Very little information is currently available about their physiological and physiopathological functions in humans. The aim of this study was to identify the possible advantage and the subsequent modification changes associated with XRN1 invalidation (siXRN1).

ORGANISM(S): Homo sapiens

PROVIDER: GSE115471 | GEO | 2020/01/14

REPOSITORIES: GEO

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mRNA expression modification after XRN1 depletion in Hela Cells

Project description:mRNA expression modification after XRN1 depletion in Hela Cells

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