Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MRNA Expression Data from Murine Hearts of Wild type (WT) C57Bl/6 mice housed under a 12h light: 12h dark or 12h light: 4h blue: 8h dark cycle for 4 weeks

ABSTRACT: Mice are on a C57Bl/6N background strain, hearts were collected at ZT07, following 4 weeks under a 12h light: 12h dark (LD) or 12h light: 4h blue: 8h dark (LBD) cycle. The microarray approach allows the investigation of gene expression changes of all genes in WT LD vs. WT LBD hearts.

ORGANISM(S): Mus musculus

PROVIDER: GSE115567 | GEO | 2018/06/12

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

mRNA Expression Data from Murine Hearts of Wild type (WT) C57Bl/6 mice housed under a 12h light: 12h dark or 12h light: 4h blue: 8h dark cycle for 4 weeks

Project description:mRNA Expression Data from Murine Hearts of Wild type (WT) C57Bl/6 mice housed under a 12h light: 12h dark or 12h light: 4h blue: 8h dark cycle for 4 weeks

| PRJNA475481 | ENA

mRNA Expression Data from Murine Hearts of Wildtype Mice over 24 hours in normal light-dark environment (12:12)

Project description:Male C57Bl/6 mice were accommodated in normal 12:12 LD condition for one week. Hearts were collected every 4 hours over 24 h starting at 1 h before lights on (ZT23) (ZT23, ZT03, ZT07, ZT11, ZT15, ZT19). The microarray approach allows the investigation of daily transcriptome-wide gene expression changes in hearts over 24 hours.

2021-07-16 | GSE180108 | GEO

mRNA Expression Data from Murine Hearts of Clock delta 19/delta 19 Mice over 24 hours in normal light-dark environment (12:12)

Project description:Male Clock delta 19/delta 19 mice were accommodated in normal 12:12 LD condition for one week. Hearts were collected every 4 hours over 24 h starting at 1 h before lights on (ZT23) (ZT23, ZT03, ZT07, ZT11, ZT15, ZT19). The microarray approach allows the investigation of daily transcriptome-wide gene expression changes in hearts over 24 hours.

2021-07-16 | GSE180109 | GEO

Colonic and cecal microbiome profiles in response to different environmental light-dark cycles

Project description:It is well known that host-microbes and immunity interactions are influenced by dietary patterns, as well as daily environmental light-dark (LD) cycles that entrain circadian rhythms in the host. Emerging data has highlighted the importance of diet patterns and timing on the interaction among circadian rhythms, gut microbiome, and immunity, however, their impacts on LD cycles are less reported. Therefore, we aim to study how LD cycles regulate the homeostatic crosstalk between gut microbiome, hypothalamic and hepatic circadian clock oscillations and immunity. We hypothesized that different environmental LD cycles: (1) constant darkness, LD0/24; (2) short light, LD8/16; (3) normal LD cycle, LD12/12; (4) long light, LD16/8; and (5) constant light, LD24/0, may affect immunity and metabolism to varying degrees. Therefore, 240 mice were managed with chow diets (CD) and antibiotics treatments (ABX) under five different LD cycles for 42 days. The colonic (co) and cecum (ce) contents were obtained for studying their impacts on gut microbiome using 16S rRNA sequencing.

2023-03-10 | GSE226852 | GEO

Synechocystis sp. PCC 6803 WT and P3 mutant microarray in mixotrophic 12h light 12h dark conditions

Project description:A microarray experiment was performed in light-dark plus glucose conditions. Samples were processed for RNA in the first hour of light and first hour of dark over two days of growth

2014-03-07 | E-MTAB-1539 | biostudies-arrayexpress

Comparative transcriptome data of multi tissues in response to different environmental light-dark cycles

Project description:It is well known that host-microbes and immunity interactions are influenced by dietary patterns, as well as daily environmental light-dark (LD) cycles that entrain circadian rhythms in the host. Emerging data has highlighted the importance of diet patterns and timing on the interaction among circadian rhythms, gut microbiome, and immunity, however, their impacts on LD cycles are less reported. Therefore, we aim to study how LD cycles regulate the homeostatic crosstalk between gut microbiome, hypothalamic and hepatic circadian clock oscillations and immunity. We hypothesized that different environmental LD cycles: (1) constant darkness, LD0/24; (2) short light, LD8/16; (3) normal LD cycle, LD12/12; (4) long light, LD16/8; and (5) constant light, LD24/0, may affect immunity and metabolism to varying degrees. Therefore, 240 mice were managed with chow diets (CD) and antibiotics treatments (ABX) under five different LD cycles for 42 days. The liver (LIV), hypothalamus (HYP), inguinal white adipose tissue (iWAT), ileum epithelium (ILE), colon epithelium (COL), jejunum epithelium (JEJ), cecum epithelium (CEC), spleen (SPL), mammary gland (MAG), and thymus gland (THY) tissues were obtained for studying their impacts immunity using RNA-Seq data.

2023-03-10 | GSE226855 | GEO

Light versus Dark gene expression in SAR11

Project description:We investigated the transcriptional response of cand. Pelagibacter ubique cultures to light and dark when grown under carbon replete and deplete conditions. Results: During exponential phase, few genes were differentially transcribed between light:dark growth conditions. In stationary phase, a high proportion (9.7%) of coding sequences were found differentially expressed between treatments; 4.7% being up-regulated in the light (n=64) and 4.9% being up-regulated in the dark (n=67). Several components of the oxidative phosphorylation pathway were up-regulated in the dark, supporting physiological data showing higher respiration rates in darkness than in the light under starvation conditions. We also observed up-regulation of a proton translocating pyrophosphate synthase (SAR11_1040), which may be an additional energy production mechanism utilized by SAR11 cells in the dark. Finally, we noted the up-regulation of pili formation genes in the array data, consistent with the observation of pili in dark grown cells via electron microscopy.

2011-12-31 | GSE24134 | GEO

Transcriptome sequencing of the hepatic samples in antibiotic-treated mice under normal light-dark cycle and short-day

Project description:Intestinal microbiota dysbiosis is related to many metabolic diseases in human health. Meanwhile, as an irregular environmental light-dark cycle, short-day (SD) may induce host circadian rhythms disturbances and worsen the risks of gut dysbiosis. Herein, we investigated how LD cycles regulate intestinal metabolism upon the destruction of gut microbes with antibiotic treatments. The transcriptome data indicated that SD have some negative effects on hepatic metabolism, endocrine, digestive, and diseases processes compared with normal light-dark cycle (NLD).The SD induced epithelial and hepatic purine metabolism pathway imbalance in ABX mice, the gut microbes, and their metabolites, all of which could contribute to host metabolism and digestion, endocrine system disorders, and may even cause diseases in the host.

2022-05-26 | GSE203566 | GEO

Transcription profiling of tomato plants at three time points in the light:dark cycle

Project description:We assayed the TOM2 microarray with target RNAs extracted from ZT0 (presumptive dawn), ZT8 (eight hours after dawn), ZT16 (presumptive dusk) and ZT20 (four hours after dusk), in Light/Dark (LD) conditions . The experimental design compared three time points to ZT0 used as a common reference: ZT8 vs. ZT0, ZT16 vs. ZT0 and ZT20 vs. ZT0. Sampling time is expressed as hours after dawn (Zeitgeber Time - ZT)

2009-04-02 | E-MEXP-1456 | biostudies-arrayexpress

Genome wide rhythmic transcription under light/dark cycles in Ostreococcus tauri

Project description:Genome wide rhythmic transcription under light/dark cycles is associated with sequential transcription of specific biological processes genes in Ostreococcus tauri. Transcriptional profiling of Ostreococcus tauri under light/dark cycles. In order to identify genes with a diurnal rhythm, cells entrained under 12:12 light/dark cycles were sampled every 3 hours for 27 hours with two overlapping time points at Time 9 (Light ON at Time 9; Light OFF at Time 21) in 3 independent experiments.

2010-04-20 | GSE16422 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data