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ChIP-Seq analysis of estrogen deprived MCF7 cells treated with H3B-5942 and standards of care compounds

ABSTRACT: The goal of this experiment was to interrogate the potential transcriptional impact of H3B-5942 by investigating its influence on genome-wide DNA-binding modes of ERa in MCF7 cells using chromatin immunoprecipitation followed by high-throughput DNA sequencing (ChIP-Seq). Affects of H3B-5942 on chromatin recruitment were compared to results from treatment with E2, 4-OHT, and fulvestrant.

ORGANISM(S): Homo sapiens

PROVIDER: GSE115607 | GEO | 2018/06/12

REPOSITORIES: GEO

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Transcriptional profiling of Ishikawa cells treated with H3B-5942, E2, or standard of care compounds

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