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Expression analysis of A375 melanoma cells with silenced BMI-1 or not

ABSTRACT: Our studies demonstrate that BMI-1 plays a crucial role in the EMT process and drug resistance in melanoma. Silencing Bmi-1 significantly inhibites the aggressive behavior and improves the chemosensitivity to all-trans retinoic acid on melanoma cells. We compared the different genes expression of A375-vector and A375-BMI-1 cells for exploring the underlying mechanisms of BMI-1 regulation on melanoma.

ORGANISM(S): Homo sapiens

PROVIDER: GSE115644 | GEO | 2021/06/01

REPOSITORIES: GEO

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