Transcriptomics

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Sequencing quantitative analysis of altered expression and Prognostic impact of LncRNAs RVT1 knockdown in glioblastoma cell lines U87


ABSTRACT: Glioblastoma multiforme (GBM) is the most malignant and lethal primary brain cancer. Despite advances in surgical resection followed by radiation and chemotherapy, the prognosis for patients with GBM remains dismal. LncRNAs regulate tumorigenesis and cancer metastasis by silencing tumor suppressors or activating oncogenes via different mechanisms, including epigenetic modification, alternative splicing, RNA decay, and post-translational modification.

ORGANISM(S): Homo sapiens

PROVIDER: GSE116531 | GEO | 2018/07/03

REPOSITORIES: GEO

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