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A robust qualitative transcriptional signature for the early diagnosis of gastric cancer

ABSTRACT: Pathological examination of gastroscopy biopsy specimens will make false diagnosis for gastric cancer (GC) due to inaccurate sampling locations and/or insufficient sampling amount. We extracted a robust qualitative transcriptional signature, based on the within-sample relative expression orderings (REOs) of gene pairs, to discriminate both GC tissues and adjacent-normal tissues from non-GC gastritis and normal gastric tissues.The qualitative transcriptional signature can be robustly applied at the individual level to aid the diagnosis of early GC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE116782 | GEO | 2018/07/10

REPOSITORIES: GEO

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