Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The profiling of gene expression in mock and fuison HBx-knockdowned cells

ABSTRACT: To comprehensively characterize the biological function of fusion HBx, the expression level of genes in mock and fusiion HBx-knockdowned cells was investigated based on microarray.

ORGANISM(S): Homo sapiens

PROVIDER: GSE117019 | GEO | 2019/12/31

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

The profiling of miRNA expression in mock and fuison HBx-knockdowned cells

Project description:To comprehensively characterize the biological function of fusion HBx, the expression level of miRNAs in mock and fusiion HBx-knockdowned cells was investigated based on microarray.

2019-12-31 | GSE117072 | GEO

The profiling of miRNA expression in mock and fuison HBx-knockdowned cells

Project description:The profiling of miRNA expression in mock and fuison HBx-knockdowned cells

| PRJNA481006 | ENA

The profiling of gene expression in mock and fuison HBx-knockdowned cells

Project description:The profiling of gene expression in mock and fuison HBx-knockdowned cells

| PRJNA480963 | ENA

The profiling of gene and miRNA expression in mock and fuison HBx-knockdowned cells

Project description:The profiling of gene and miRNA expression in mock and fuison HBx-knockdowned cells

| PRJNA481001 | ENA

Wild-type versus HBx-transfected mive

Project description:Hepatitis B virus (HBV) has been clearly recognized as an etiological factor for hepatocellular carcinoma (HCC). HBV encodes the potentially oncogenic HBx protein. We aimed to elucidate the molecular mechanism of HCC caused by HBx and to discover the biomarker related to HCC by HBx. Three experimental groups, 3, 9 and 13 month aged HBx Tg mice and age matched normal wild type B6 mouse which have same background of HBx Tg mice were used to find differentially expressed genes during HCC. Keywords: Genetic modification 3-month-old, 9-month-old, 13-month-old wild type B6 mice vs 3-month-old, 9-month-old, 13-month-old HBx transfected mice; Biological replicates at each timepoint; 9 controls vs 9 HBx-mice

2010-06-19 | E-GEOD-12723 | biostudies-arrayexpress

LncRNAs expression profiles in the livers of 20-month-old male HBx transgenic mice and C57BL/6 wild-type mice

Project description:The hepatitis B virus X protein (HBx) has been implicated as an oncogene in both epigenetic modifications and genetic regulation during hepatocarcinogenesis, but the underlying mechanisms are not entirely clear. Long non-coding RNAs (lncRNAs), which regulate gene expression with little or no protein-coding capacity, are involved in diverse biological processes and in carcinogenesis. We asked whether HBx could promote hepatocellular carcinoma (HCC) by regulating the expression of lncRNAs.In this study, we investigated the alteration in expression of lncRNAs induced by HBx using microarrays, and our results indicate that HBx transgenic mice have a specific profile of liver lncRNAs compared with wild-type mice.

2013-11-04 | GSE42185 | GEO

HBX-HepG2 versus Control-HepG2

Project description:Mature microRNA expression profiling of HBx-expressing HepG2 cells versus Control cells under UV stress The mature microRNA expression profile of HBx-expressing HepG2 cells versus control cells in three independent biological repeated experiments. This study focuses only on human sequences. The complete data matrix is linked below as a supplementary file.

2010-05-16 | E-GEOD-15554 | biostudies-arrayexpress

HBX-HepG2 versus Control-HepG2 (no UV)

Project description:Mature microRNA expression profiling of HBx-expressing HepG2 cells versus Control cells. Free of UV sensitization. The mature microRNA expression profile of HBx-expressing HepG2 cells versus control cells in three independent biological repeated experiments (no UV). This study focuses only on human sequences. The complete data matrix is linked below as a supplementary file.

2010-05-24 | E-GEOD-17474 | biostudies-arrayexpress

Wild-type versus HBx-transfected mive

2008-09-11 | GSE12723 | GEO

Expression data from Hela cells stably expressing the wild-type HBx and the four mutant HBx

Project description:In large cohort studies, several HBx mutants were identified as independent risk factors for HCC risk.In order to study the carcinogenic mechanism between different mutants, HeLa cell lines expressing wild type and different mutated HBx proteins were constructed. We used microarrays to describe gene expression in HeLa cells stably expressing the wild-type HBx and the four mutant HBx, and to identify distinct classes of up-regulated genes.

2022-03-02 | GSE179126 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data