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Genome-wide DNA methylation change due to H19 knockdown and TET3 knockdown in UtLM

ABSTRACT: We used Methyl-MiniSeq platform from Zymo Research company to identify genome-wide methylation changes affected by H19 knockdown and TET3 knockdown in human UtLM. Following H19 and TET3 knockdown, we observed extensive genome-wide methylation pattern changes relative to siCon cells, with some genes showing increased methylation, others showing decreased methylation, and a third group with no significant change.

ORGANISM(S): Homo sapiens

PROVIDER: GSE117190 | GEO | 2021/07/16

REPOSITORIES: GEO

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